Métricas para osteoartrite

A osteoartrite (OA) é uma das doenças reumáticas mais comuns, sendo importante causa de dor crônica, incapacidade e redução da qualidade de vida. A padronização de métricas de avaliação da morbidade ocasionada por esta doença é indispensável para a realização de estudos clínicos, ainda que seu uso no dia a dia seja menos frequente na prática do reumatologista. Para este fim, as métricas precisam demonstrar validade e reprodutibilidade, além de avaliar os domínios principais de acometimento da doença. Nesse contexto, vários índices de avaliação surgiram nas últimas décadas.

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Parecer Científico da Comissão de Osteoartrite da Sociedade Brasileira de Reumatologia sobre o uso do Plasma Rico em Plaquetas (PRP) para o tratamento da Osteoartrite de Joelho e Quadril.

Alguns agentes biológicos têm sido testados no tratamento da osteoartrite, entre os quais o plasma rico em plaquetas (PRP), para uso intra-articular.

Continue lendoParecer Científico da Comissão de Osteoartrite da Sociedade Brasileira de Reumatologia sobre o uso do Plasma Rico em Plaquetas (PRP) para o tratamento da Osteoartrite de Joelho e Quadril.

Saiba o que é a Artrite Reumatoide Inicial e quando você deve procurar um médico.

O diagnóstico precoce e o início imediato do tratamento são fundamentais para o controle da atividade da artrite reumatoide, para evitar a incapacidade funcional e lesão articular causadas pela doença e garantir o retorno ao estilo de vida normal do paciente o mais rapidamente possível.

Continue lendoSaiba o que é a Artrite Reumatoide Inicial e quando você deve procurar um médico.

Reference range of serum uric acid and prevalence of hyperuricemia: a cross-sectional study from baseline data of ELSA-Brasil cohort

Background: Most of the few studies that have established reference ranges for serum uric acid (SUA) have not taken into account factors which may interfere with its levels and followed rigorous…

Continue lendoReference range of serum uric acid and prevalence of hyperuricemia: a cross-sectional study from baseline data of ELSA-Brasil cohort

Phenotypes in Osteoarthritis: Why Do We Need Them and Where Are We At?

This article is part of the Osteoarthritis issue for the Clinics in Geriatric Medicine journal. It covers the main aspects related to research and clinical practice of osteoarthritis phenotyping, including the concepts, the rationale for studies of OA phenotypes and their history, the approaches to OA phenotyping, recent advances in this area, and future directions.

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Leia mais sobre o artigo Efficacy of platelet-rich plasma and plasma for symptomatic treatment of knee osteoarthritis: a double-blinded placebo-controlled randomized clinical trial
ARTIGO-01

Efficacy of platelet-rich plasma and plasma for symptomatic treatment of knee osteoarthritis: a double-blinded placebo-controlled randomized clinical trial

Platelet-rich plasma (PRP) has a still conflicting efficacy for knee osteoarthritis (KOA) and might be a minimally invasive and safe treatment alternative. The potential benefit of only plasma (non-enriched) has never been investigated. Our aim was to evaluate the efficacy of intra-articular platelet-rich plasma (PRP) and plasma to improve pain and function in participants with KOA over 24 weeks.

Continue lendoEfficacy of platelet-rich plasma and plasma for symptomatic treatment of knee osteoarthritis: a double-blinded placebo-controlled randomized clinical trial

Calcium Pyrophosphate Deposition Disease in the Craniovertebral Junction: An Unusual Cause of Neck Pain

Crowned Dens Syndrome (CDS) is a rare manifestation of Calcium Pyrophosphate Deposition (CPPD) disease characterised by calcification around the odontoid process in the atlantoaxial joint. It manifests as intense neck pain with signs of systemic inflammation, including elevated acute phase reactants.

Continue lendoCalcium Pyrophosphate Deposition Disease in the Craniovertebral Junction: An Unusual Cause of Neck Pain

Association of baseline and change in tibial and femoral cartilage thickness and development of widespread full-thickness cartilage loss in knee osteoarthritis – data from the Osteoarthritis Initiative

Objective: To investigate whether baseline cartilage thickness and its longitudinal change are associated with incident widespread full-thickness cartilage loss (wsFTCL) in knee osteoarthritis, and whether there are optimal cut-off values for predicting wsFTCL.

Continue lendoAssociation of baseline and change in tibial and femoral cartilage thickness and development of widespread full-thickness cartilage loss in knee osteoarthritis – data from the Osteoarthritis Initiative